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N-Cyclopropylpemoline (also known as Cyclazodone) is a novel stimulant substance of the 4-oxazolidinone class that produces stimulating and focus enhancing effects when administered. It is structurally related to pemoline and 4-methylaminorex.
Cyclazodone was developed in the 1960s by the American Cyanamid Company. Its non-clinical use has only found recent attention as a research chemical study aid.
It should be noted that the lack of pharmacological data and extremely limited history of human usage pose considerable concern regarding its long-term use as a substitute for prescription stimulants. Order Cyclazodone online
Cyclazodone has no documented history of recreational human usage before it appeared on the online research chemical market in 2017.
Based on related compounds, it is speculated that it likely possesses hepatotoxic and other not-yet-known toxic properties. It is strongly advised to use harm reduction practices if using this substance. Purchase Cyclazodone in bulk online
|Chemical class||Substituted aminorex|
Cyclazodone dosage table
|Light||5 â€“ 15 mg|
|Common||15 â€“ 25 mg|
|Strong||25 â€“ 40 mg|
|Heavy||40 mg + Liver damage may result from heavy or sustained usage.|
Cyclazodone effect progress
|Total||5 â€“ 7 hours|
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Cyclazodone is a phenyl 4-oxazolidinone that differs from the parent pemoline by an N-cyclopropyl group.
Compounds like cyclazodone of the 4-oxazolidinone class can be considered as 4-oxy derivatives of the 2-amino-5-aryloxazoline class including aminorex, fluminorex, and 4-methylaminorex, conformationally restricted analogues of phenethylamines and amphetamines.
Cyclazodone is structurally most closely related, not to pemoline, but rather to two N-substituted derivatives of pemoline fenozolone (N-ethyl pemoline) and thozalinone (N,N-dimethyl pemoline).
Cyclazodone is an amphetamine-like agonist of the Trace Amine Associated Receptor 1 (TAAR1), which is a key regulator of common and trace brain monoamines such as dopamine, serotonin and noradrenaline.
The agonism of this set of receptors results in the release of increased concentrations of dopamine, serotonin and noradrenaline in the synaptic cleft. This leads to cognitive and physical stimulation within the user. How to buy Cyclazodone and pay with bitcoin
The toxicity and long-term health effects of recreational cyclazodone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because cyclazodone has a very limited history of human usage.
Another compound related in structure, 4-methylaminorex, is associated with pulmonary hypertension; though, it is reported to induce far stronger stimulation than that of cyclazodone.
The structurally related compound pemoline was removed from the market after it was found to cause liver damage in children. How to buy Cyclazodone and pay with bitcoin
In rodents and primates, sufficiently high doses of monoamine releasing agents cause dopaminergic neurotoxicity, or damage to dopamine neurons, which is characterized by reduced transporter and receptor function.
There is no evidence that releasing agents are directly neurotoxic in humans. However, large doses of releasing agents may cause indirect neurotoxicity as a result of increased oxidative stress from reactive oxygen species and autoxidation of dopamine.
It is strongly recommended that one use harm reduction practices when using this substance.
Addiction is a serious risk with heavy recreational stimulant use but is unlikely to arise from typical long-term medical use at therapeutic doses.
Notably, the structurally related compound pemoline fails to demonstrate a potential for self-administration in primates and is considered to have reduced risk of dependence relative to those more typical dopaminergic stimulants. Caution is nonetheless advised, as with other monoamine releasing agents. Where to get cyclazodone online
Tolerance to many of the effects of cyclazodone develops with prolonged and repeated use. This results in users having to administer increasingly large doses to achieve the same effects.
After that, it takes about 3 â€“ 7 days for the tolerance to be reduced to half and 1 â€“ 2 weeks to be back at baseline (in the absence of further consumption). Cyclazodone presents all dopaminergic stimulants, meaning that after the consumption of amphetamine all stimulants will have a reduced effect. Where to get cyclazodone online
Based on its pharmacological similarity to other stimulants, it is likely that misuse of this compound can result in state of psychosis marked by a variety of symptoms (e.g., paranoia, hallucinations, orÂ delusions).
A review on the treatment for amphetamine and methamphetamine abuse-induced psychosis states that about 15% of users fail to recover completely.
The same review asserts that based upon at least one trial, antipsychotic medications effectively resolve the symptoms of acute amphetamine psychosis. Psychosis very rarely arises from therapeutic use.
The combination of the prolonged use of high doses combined with sleep deprivation significantly increases the risk of stimulant psychosis. Order Cyclazodone online
Cyclazodone is currently a gray area compound within all parts of the world, meaning its regulation lies in a legal gray area and that it is not known to be specifically illegal (œscheduled) within any country. Order Cyclazodone online
However, people may still be charged for its possession under certain circumstances such as under analogue laws and with intent to sell or consume. It is a banned stimulant under the World Anti-Doping Agency prohibited list.
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