About U47700
What is U-47700?
The drug U-47700 is a synthetic analgesic opioid. It was first synthesized in 1978 by an employee of the Upjohn Company. References to U-47700 began appearing in academic literature in 1982, when research conducted by Upjohn was first published. U-47700 normally appears as a white powder or a liquid and can be used orally, intravenously, nasally, or inhaled. “U4”, “pink”, and “fake morphine” are common street names for this drug. However, it has around 7.5 times the potency of morphine in animal models.
U-47700 acts as an agonist on the mu-opioid receptors in the central nervous system. This causes effects similar to other opioids such as euphoria, analgesia, and extreme sedation. It depresses the cough reflex, and constricts pupils, and can suppress the respiratory system to potentially fatal levels. Users may also experience itchiness, drowsiness, nausea, cyanosis, or constipation.
Physical Appearance
White powder is supplied by some online vendors; one vendor supplies U- 47700 as a liquid for use in inhalers in which a user reported that the liquid tasted “minty”
perhaps because of adulterants.
What is it used for?
Originally, U-47700 was developed to be a non-addicting analgesic as potent as morphine; however the drug was never brought to market and has not been studied in humans. There is little pharmacokinetic data available and it is not approved for any medical use in humans or veterinary practice.
Detection in biological fluids
U-47700 may be measured in serum, plasma, blood or urine to monitor for abuse, confirm a diagnosis of poisoning, or assist in a medicolegal death investigation. Serum or blood U-47700 concentrations are expected to be in a range of 10-250 μg/L in intoxicated patients and 100-1500 μg/L in deceased victims of acute overdosage. The analysis usually involves liquid chromatography-mass spectrometry.
