JWH018 Research Chemicals Online

SGT-151(Cumyl-PeGACLONE)

SGT-151
(Cumyl-PeGACLONE)

Available
10g........$150
50g...…..$230
100g......$400
500g......$1200
1000g....$2000
SGT-151

SGT-151(Cumyl-PeGACLONE)

SGT-151 was specifically designed to circumvent German generic legislative approaches (NpSG) to control ‘cannabimimetics/synthetic cannabinoids’. Nevertheless, the aim was to prohibit indole, indazole, and benzimidazole core structures in November 2016.

Also, it is not the first time that substances have been exclusively designed to evade generic definitions in national laws. It was reported that synthetic cannabinoid receptor agonist constituents of Spice were classified in the UK as Class B agents. This was in December 2009.

By the first quarter of 2017, Cumyl-PeGACLONE had been detected in 23% and 45% of test purchased herbal blends in Germany. SGT-151 was detected at concentrations between 15-74 mg/g; average 39 mg/g.

As has been seen with other core structures, it is reasonable to anticipate the emergence of analogues. There is potential for modification of the structure at the R1-R5 positions, or a combination.

Reports of 5F-Cumyl-PeGACLONE are already emerging. We postulate three other potential analogues and propose nomenclature. Other analogues are possible.

Following pharmacological evaluation, Cumyl-PeGACLONE demonstrated full agonistic activity and high potency at both CB1 and CB2 receptors. In vitro and in vivo phase I metabolism studies have shown Cumyl-PeGACLONE to be extensively metabolized.
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