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Lorazepam (Ativan)

About Lorazepam (Ativan)

What is lorazepam (Ativan) & How does it work?

Lorazepam (Ativan) is thought that excessive activity of nerves in the brain may cause anxiety and other psychological disorders. Gamma-aminobutyric acid (GABA) is a neurotransmitter, a chemical that nerves in the brain use to send messages to one another that reduces the activity of nerves in the brain.

It is thought that lorazepam and other benzodiazepines may act by enhancing the effects of GABA in the brain to reduce activity. Because lorazepam is removed from the blood more rapidly than many other benzodiazepines, there is less chance that lorazepam concentrations in blood will reach high levels and become toxic.

Lorazepam also has fewer interactions with other medications than most of the other benzodiazepines.

What are the uses for lorazepam?

Ativan (lorazepam) is used for the management of anxiety disorders, the short-term relief of symptoms of anxiety or anxiety associated with depression.

Ativan is effective for panic attacks, short-term and long-term treatment of insomnia  and is used in combination with other medications to prevent nausea and vomiting resulting from chemotherapy.

Ativan also is administered before anesthesia for sedation and used for prevention and treatment of alcohol withdrawal.
It also is used for treating seizures (status epilepticus)

What is the dosage for lorazepam?

The dose of lorazepam is tailored to the patient's needs.

The usual dose for treating anxiety is 2-6 mg orally every 8 to 12 hours as needed.

Insomnia is treated with 2-4 mg given at bedtime.
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